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TNF superfamily / by Sanjay V. Khare.

By: Khare, Sanjay [author.].
Material type: materialTypeLabelBookPublisher: Boca Raton, FL : CRC Press, an imprint of Taylor and Francis, 2007Edition: First edition.Description: 1 online resource (100 pages) : 9 illustrations.Content type: text Media type: computer Carrier type: online resourceISBN: 9781498713252; 1498713254; 9780429089176; 0429089171.Subject(s): Tumor necrosis factor | Tumor Necrosis Factors | SCIENCE / Life Sciences / Biology / General | SCIENCE / Life Sciences / GeneralDDC classification: 616.079 Online resources: Taylor & Francis | Taylor & Francis | OCLC metadata license agreement
Contents:
Chapter 1 CD40 and CD154 -- chapter 2 Regulation of T Cell Immunity by OX40 and OX40L -- chapter 3 Signal Transduction in Osteoclast Biology: The OPG-RANKL-RANK Pathway -- chapter 4 Tumor Necrosis Factor (TNF) and Neurodegeneration -- chapter 5 The Role of LIGHT in Autoimmunity -- chapter 6 CD137 Pathway in Innate and Adaptive Immunity.
Abstract: The tumor necrosis factor/receptor [TNF/TNFR] superfamily consists of more than 20 transmembrane proteins with conserved N-terminal cysteine-rich domains [CRDs] in the extracellular ligand binding region. Members have wide tissue distribution and play important roles in biological processes such as lymphoid and neuronal development, innate and adaptive immune response, and cellular homeostasis. The chapters of this book address some of the most interesting functions of the TNF/TNFR superfamily.
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Chapter 1 CD40 and CD154 -- chapter 2 Regulation of T Cell Immunity by OX40 and OX40L -- chapter 3 Signal Transduction in Osteoclast Biology: The OPG-RANKL-RANK Pathway -- chapter 4 Tumor Necrosis Factor (TNF) and Neurodegeneration -- chapter 5 The Role of LIGHT in Autoimmunity -- chapter 6 CD137 Pathway in Innate and Adaptive Immunity.

The tumor necrosis factor/receptor [TNF/TNFR] superfamily consists of more than 20 transmembrane proteins with conserved N-terminal cysteine-rich domains [CRDs] in the extracellular ligand binding region. Members have wide tissue distribution and play important roles in biological processes such as lymphoid and neuronal development, innate and adaptive immune response, and cellular homeostasis. The chapters of this book address some of the most interesting functions of the TNF/TNFR superfamily.

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