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Multi-scale Extracellular Matrix Mechanics and Mechanobiology [electronic resource] / edited by Yanhang Zhang.

Contributor(s): Zhang, Yanhang [editor.] | SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Studies in Mechanobiology, Tissue Engineering and Biomaterials: 23Publisher: Cham : Springer International Publishing : Imprint: Springer, 2020Edition: 1st ed. 2020.Description: XIII, 392 p. 126 illus., 107 illus. in color. online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9783030201821.Subject(s): Biomedical engineering | Biophysics | Mechanics, Applied | Solids | Biomedical Engineering and Bioengineering | Biophysics | Solid MechanicsAdditional physical formats: Printed edition:: No title; Printed edition:: No title; Printed edition:: No titleDDC classification: 610.28 Online resources: Click here to access online
Contents:
Contributions of extracellular (ECM) constituents to the mechanical function of soft biological tissue -- Structure-based constitutive modeling of ECM mechanics -- Advanced optical imaging of ECM structures in biological systems –fundamental research and clinical applications -- Discrete fiber network modeling of ECM networks -- Microstructural mechanisms and contributions of elastin and collagen to the elastic and viscoelastic behavior of soft biological tissues -- Scale-dependency of multi-scale ECM mechanics and measurements -- Bridging scales - multi-scale mechanics of engineered and native tissue -- Mechanical and biological interactions between cells and ECM -- Multi-physics modeling of ECM mechanics.
In: Springer Nature eBookSummary: This book describes the current state of knowledge in the field of multi-scale ECM mechanics and mechanobiology with a focus on experimental and modelling studies in biomechanical characterization, advanced optical microscopy and imaging, as well as computational modeling. This book also discusses the scale dependency of ECM mechanics, translation of mechanical forces from tissue to cellular level, and advances and challenges in improving our understanding of cellular mechanotransduction in the context of living tissues and organisms.
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Contributions of extracellular (ECM) constituents to the mechanical function of soft biological tissue -- Structure-based constitutive modeling of ECM mechanics -- Advanced optical imaging of ECM structures in biological systems –fundamental research and clinical applications -- Discrete fiber network modeling of ECM networks -- Microstructural mechanisms and contributions of elastin and collagen to the elastic and viscoelastic behavior of soft biological tissues -- Scale-dependency of multi-scale ECM mechanics and measurements -- Bridging scales - multi-scale mechanics of engineered and native tissue -- Mechanical and biological interactions between cells and ECM -- Multi-physics modeling of ECM mechanics.

This book describes the current state of knowledge in the field of multi-scale ECM mechanics and mechanobiology with a focus on experimental and modelling studies in biomechanical characterization, advanced optical microscopy and imaging, as well as computational modeling. This book also discusses the scale dependency of ECM mechanics, translation of mechanical forces from tissue to cellular level, and advances and challenges in improving our understanding of cellular mechanotransduction in the context of living tissues and organisms.

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